Is it safe to take codeine after a colonoscopy?

Like morphine and heroin, codeine is a narcotic. These drugs decrease the peristaltic contractions of the large intestine. This increases water absorption but can lead to constipation. There may be the chance of inflammation if there is material in the large intestine, but as I understand, as much material is emptied as possible from the large intestine prior to the colonoscopy. If you want to take a narcotic to alleviate pain, I would avoid eating after both the colonoscopy and taking any narcotics. My advice is to discuss this with your doctor.